Mexico has qualified to seventeen World Cups and has qualified consecutively since 1994, making it one of six countries to do so. The Mexico national team, along with Brazil are the only two nations to make it out of the group stage over the last seven World Cups. Mexico's best progression in World Cups has been reaching the quarter-finals in both the 1970 and 1986 World Cups, both of which were staged on Mexican soil.

Mexico is historically the most successful national team in the CONCACAF region, having won eleven confederation titles, including eight CONCACAF Gold Cups and three CONCACAF Championships (the precursor to the Gold Cup), as well as two NAFC Championships, one North American Nations Cup, one CONCACAF Cup and two gold medals of the Central American and Caribbean Games.